Microbiome

Microbial Pathogenesis

Microbial pathogenesis is the ability of a microorganism or its components to cause infection in a host after forming a complex pattern of interactions between host and pathogen. Pathogenicity is the ability of a pathogen to produce disease. Pathogenicity is expressed by microorganisms using their virulence or the degree of pathogenicity of microorganisms. The genetic, biochemical, and structural features that contribute to a pathogen's ability to cause disease are known as determinants of its virulence. Pathogens enter the body through entrances and exit through exits. The pathogenic stages include exposure, adhesion, invasion, infection, and dissemination.

Pathogenic mechanism       

• Bacterial infectivity
• host resistance
• Genetic and molecular basis of virulence
• host-mediated pathogenesis
• intracellular growth