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6th Global Summit on Microbiome, will be organized around the theme “Theme: Technologies of Beneficial Microbes for human and animal health”

Microbiome-2023 is comprised of keynote and speakers sessions on latest cutting edge research designed to offer comprehensive global discussions that address current issues in Microbiome-2023

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Microbiome epidemiology still suffers from measurement and population heterogeneity, method standardization and authority issues. However, its mechanistic interpretation has already been very successful in settings ranging from drug metabolism to immunity. Measuring the composition of the Microbiome (which taxa/species are present) is most commonly addressed using amplicon-based/marker gene sequencing approaches to conduct microbial populations [45, 46] across a variety of samples and treatments. An imbalance of the normal gut Micro biome is associated with a wide range of systemic manifestations of gastrointestinal conditions such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) and diseases such as obesity, type-2 diabetes and autopsy.


Phytochemicals, also called phytonutrients, are potentially helpful compounds found in plant foods. It may help prevent chronic diseases, including cancer. These can be found in vegetables, fruits, beans, grains, nuts and seeds. However, the types and amounts of phytochemicals in different plants vary. Some examples of well-known phytochemicals are flavonoids, phenolic acids, isoflavones, curcumin, isothiocyanates, and carotenoids. The safest sources of phytochemicals are in their natural form, such as fruits and vegetables. Phytochemicals are found in a variety of plants that are frequently included in the human diet and are generally considered safe to consume because they are naturally occurring.


The Microbiome influences the systemic immune response, influencing the outcome of various diseases. Manipulation of these microbial factors can induce useful immune responses to alleviate disease. The Microbiome influences the systemic immune response that influences the growth of various diseases. Manipulation of these microbial factors can alleviate complaints by shifting useful and vulnerable responses into Microbiome manipulation. Generally, FMT involves the management of therapeutic microbial populations. FMT is a beneficial system that replaces disease-causing microorganisms with beneficial ones. It involves the transfer of healthy microbes from healthy donor to donor via a color mode of transfer.


Microbial pathogenesis is the ability of a microorganism or its components to cause infection in a host after forming a complex pattern of interactions between host and pathogen. Pathogenicity is the ability of a pathogen to produce disease. Pathogenicity is expressed by microorganisms using their virulence or the degree of pathogenicity of microorganisms. The genetic, biochemical, and structural features that contribute to a pathogen's ability to cause disease are known as determinants of its virulence. Pathogens enter the body through entrances and exit through exits. The pathogenic stages include exposure, adhesion, invasion, infection, and dissemination.

Pathogenic mechanism       

A virome refers to the collection of viruses that are typically studied and characterized by met genomic sequencing of viral nucleic acids found to be associated with a specific ecosystem, organism, or holo biotic. The term is often used to describe environmental viral shotgun Meta genomics. The development of high-throughput sequencing technologies has revealed that the human gut Microbiome is a complex community in which the virome plays a crucial role in regulating gut immunity and homeostasis. This collection of viruses is called the "human virome". It can also be defined as the viral component of the human Microbiome, including viruses that can cause infection or latent infection, as well as viruses that integrate into the human genome, Human papillomavirus.


Taxonomy is the classification, nomenclature and identification of microorganisms (algae, protozoa, slime molds, fungi, bacteria, archaea and viruses). The naming of organisms by genus and species is governed by international norms. Microbial taxonomy includes identification of isolates as known species, classification of new isolates (creation of new taxa), and nomenclature. Taxonomy applies to all living organisms, providing a consistent method to classify, name and identify organisms. This consistency allows biologists around the world to use a common label for every organism studied across numerous biological disciplines. Taxonomy is divided into three parts: (1) classification, (2) nomenclature, and (3) identification. There are naming rules, but no classification or identification rules. Microbial taxonomy is a method by which microorganisms can be grouped together. Organisms that share similarities in the criteria used belong to the same group and are separated from other Microbiomes with different characteristics. There are many classification criteria that can be used.


Soil organisms and plants interact through the root system as a symbiotic relationship, where microbial communities are mutually beneficial, growth and plant demand for nutrients to produce biomass. Rhizosphere microbes interact continuously, leading to symbiotic, parasitic, symbiotic, saprotrophic, and symbiotic relationships. These organisms affect above-ground activities and are part of the bulk soil species. These organisms affect above-ground activities and are part of the bulk soil species. In the root zone of the soil environment, the contact between microorganisms and the root system involves a series of activities that contribute to plant growth. This soil-microbe interaction plays an important role in enhancing plant bioavailability and mineral nutrient uptake.


Micronutrients are very small amounts of vitamins and minerals that the body needs. However, their effects on physical health are crucial, and a deficiency in any of them can lead to serious and even life-threatening conditions. Soils provide relatively large amounts of nitrogen, phosphorus, potassium, calcium, magnesium and sulfur; these are often referred to as macronutrients. Soils provide relatively small amounts of iron, manganese, boron, molybdenum, copper, zinc, chlorine and cobalt, so-called trace elements. The remaining essential nutrients extracted from the soil are called micronutrients because they are required in small quantities. They are boron (B), chloride (Cl), copper (Cu), iron (Fe), manganese (Mn), molybdenum (Mo), nickel (Ni) and zinc (Zn).


Plant transformation vectors are plasmids specifically designed to facilitate the production of transgenic plants. Binary vectors are a standard tool for Agrobacterium tumefaciens-mediated transformation of higher plants. It consists of T-DNA borders, multiple cloning sites, and replication functions in E. coli. Ti plasmid is the most commonly used natural vector for plant gene cloning. In plant genetic engineering, Ti plasmids can be used to carry foreign genes into plant cells. The Ti plasmid is the virulence factor of the soil-borne bacterium Agrobacterium tumefaciens. Applications of virus-based vectors include the production of human/animal therapeutic proteins in plant cells, and the specific study of plant biochemical processes, including those conferring resistance to pathogens.


In addition to viruses, four groups of organisms make up the soil microbial community. They are bacteria, actinomycetes, fungi and algae. Each of these groups consists of many genera and hundreds of species. Soil flora includes bacteria, fungi and algae and tends to be more stable. On the other hand, once the food source is exhausted, the fauna will move around. Fauna includes protozoa, nematodes, springtails and mites. Soil fauna and flora are the basic building blocks of all soils. Of particular importance are their roles in the retention, decomposition and incorporation of plant debris, nutrient cycling and their effects on soil structure and porosity.


The microbiota is the range of microorganisms that may be commensal, commensal or pathogenic those are found in and on all multicellular organisms, including plants. The human body contains many microorganisms, including a large number of bacteria, viruses, fungi and protozoa, collectively known as the microbiota. Compared to the number of cells that make up the human body, the number of micro biota has been found to be much larger. A normal gut microbiota has specific functions in host nutrient metabolism, xenobiotic and drug metabolism, maintenance of the structural integrity of the intestinal mucosal barrier, immune regulation, and defense against pathogens. The human Microbiome consists of the 10-100 trillion commensal microbial cells in each human body, primarily bacteria in the gut; the Human Microbiome consists of the genes carried by these cells.


The Marine Microbiome is the sum total of microorganisms and viruses in the ocean and any related environment, including seafloor and marine flora and fauna. The still quantified and largely unknown diversity of microbial life may be a hidden treasure of human society. Marine microbes play many important roles in Earth systems: they influence our climate, are major primary producers in the oceans, govern much of the flow of energy and nutrients in the oceans, and provide us with a source of medicines and natural products. They include bacteria, viruses, archaea, protists and fungi. Marine microbes are tiny single-celled organisms that live in the oceans and make up more than 98% of the ocean's biomass.


The Human Microbiome is the aggregate of all microbiota residing on or in human tissues and bio fluids together with the corresponding anatomical sites where they are located, including skin, mammary glands, seminal fluid, uterus, ovarian follicles, lungs, saliva, mucosa conjunctiva, bile duct, and digestive tract. The Microbiome is the genetic material of all the microbes - bacteria, fungi, protozoa, and viruses - that live on and in the human body. The number of genes in all the microbes in one person's Microbiome is 200 times the number of genes in the human genome. These organisms affect human physiology, in both health and disease, contributing to the enhancement or disturbance of metabolic and immune functions. Newborns get their first Microbiome from their mother at birth. During that trip, the newborn is completely covered in bacteria, giving him a new Microbiome.


Holobiotics are collections of closely related species with complex interactions, such as plant species and their Microbiome members. Every species that exists in a whole organism is an organism, and the genomes of all organisms taken together are the whole genome, or the "comprehensive genetic system" of the whole organism. A whole-organism perspective is essential to capture within a single interpretive unit the important niche-building processes that occur at these different levels and across multiple species. Humans, animals and plants are all holographic beings. This concept is now supporting a growing number of scientific projects ranging from studies of the environment, animal or plant ecosystems, to studies of immunity, nutrition and human health.


The gut microbiota, gut microbiome or gut flora is the microorganisms that live in the digestive tract of animals, including bacteria, archaea, fungi and viruses. The gastrointestinal meta genome is the collection of all genomes of the gut microbiota. The gut is the main home of the Human Microbiome. The gut microbiota consists of the trillions of microbes and their genetic material that live in the gut. Consisting mostly of bacteria, these microbes participate in functions that are critical to your health and well-being. With the right healthy habits (diet, exercise, sleep, and stress management—and supplements if necessary), building a healthy Microbiome can take up to 6 months, but it truly is a lifelong journey. You need to continue these habits to maintain a healthy Microbiome.